Immunology RSS Feeds

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studyfinds.com2d ago

Autoantibodies identified as potential direct drivers of long COVID symptoms in subset of patients

cell.com6d ago

Study finds causal link between autoantibodies and neurological symptoms in long COVID

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cell.com6d ago

Study reveals virus-reactive T cells and local cytokine activation drive kidney inflammation in lupus nephritis

Proliferative lupus nephritis (LN) is triggered by deposition of autoantibodies in glomeruli and paralleled by a T cell–rich kidney infiltrate. Although these T cells have been attributed to the pr...

science.org·Science·7d ago·14 min read

ADAM17-mediated AIR motif enables T cell-autonomous control of CAR signaling and receptor shedding

AIR, a minimal 15-amino acid motif, enables rapid, activation-dependent shedding of surface receptors through ADAM17, allowing T cells to autonomously tune receptor expression. AIR reduces tonic CAR signaling and exhaustion, limits activation-induced cell

Insightsciencehealthbiotechnologycell.com·Science·9d ago·73 min read

Study reveals partially sequential class-switch recombination with IGHG2 checkpoint in primary human antibody response to vaccination

Using the SARS-CoV-2 mRNA vaccine as a model immune challenge, Montamat-Garcia et al. describe how antibody class-switch recombination (CSR) during a primary human response is partially sequential, but with checkpoint at the IGHG2 locus. Moreover, CSR is

Insightsciencehealthimmunologycell.com·Science·10d ago·71 min read

Nociceptive sensory nerves suppress anti-tumor immunity by blocking tertiary lymphoid structure formation in lung cancer

cell.com10d ago

Ladasten Reverses Depression-Like Behavior and T-Cell Imbalances in Social Defeat Mouse Model

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scirp.org11d ago

Metabolically engineered probiotic nanovaccine shows sequential immunomodulation for chronic MRSA bone infection treatment

cell.com13d ago

Systematic mapping of CD4+ T cell epitopes in Nipah and measles viruses reveals cross-reactive immune targets for vaccine development

cell.com13d ago

Single mild gut infection increases blood-brain barrier permeability and triggers brain inflammation in Parkinson's disease mouse model

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journals.plos.org16d ago

Study reveals how immunotherapy can drive immune evasion in pancreatic cancer through Treg cell activity and MHC-I suppression

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scim.ag16d ago

Study reveals how immunotherapy can drive immune evasion in pancreatic cancer through Treg cell activity and MHC-I suppression

Mechanisms driving immunotherapy resistance in pancreatic cancer are poorly defined. We demonstrate that programmed death-ligand 1 immune checkpoint blockade promoted immune evasion by epigenetic T...

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scim.ag·Twitter Science (trending)·20d ago·22 min read

DGKζ kinase is essential for CD40-mediated B cell immune synapse formation and antibody production

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scim.ag20d ago

Fungal metabolite IM502 reprograms tumor-associated macrophages to enhance anti-cancer immunity

cell.com21d ago

Aging impairs antibody responses through defective T follicular helper cell maturation, not B cell dysfunction

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cell.com21d ago

Intestinal IgA found necessary and sufficient for clearing norovirus in mouse model