Mouse study: Plant-based 'longevity diet' with occasional fish reduces body fat and frailty without calorie restriction
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Summary
A new mouse study published in Cell Metabolism by USC researchers found that a 'longevity diet' — mostly vegan with some fish — reduced body fat and frailty in older mice without calorie restriction. The diet, which cycles between a fasting-mimicking diet and a plant-based regimen with occasional fish, outperformed Western, keto, and other diets. Mice on this diet ate more than those on other diets yet lost the most body fat while preserving muscle, and performed better on strength and balance tests. The key mechanism appears to be methionine restriction — an amino acid abundant in meat and low in plant proteins — which triggered beneficial metabolic changes including increased growth hormone and GLP-1 levels.
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Key quotes
· 3 pulledLosing weight is supposed to come down to one rule: eat less than the body burns. A new mouse study suggests that rule misses something.
Older mice on one diet ate more than mice on the Western and keto diets, yet still lost the most body fat without losing muscle.
The difference was not how much they ate, but what.
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