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Mouse Study Links Protein TTP to Improved Strength and Reduced Frailty in Aging

By

Ivan Farkas

9d ago· 5 min readenNews

Summary

Researchers at the University at Buffalo identified the protein tristetraprolin (TTP) as a potential target for reducing age-related frailty and bone loss. In a study on mice, boosting TTP levels led to improved grip strength, walking ability, endurance, and overall physical performance. The protein helps keep inflammation in check, suggesting a possible pathway for developing therapies to ease aging effects in humans, though the evidence is currently limited to animal models.

Key quotes

· 1 pulled
Boosting TTP in aging mice resulted in 'better grip strength, better walking, endurance, and overall physical performance'
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A protein that helps keep inflammation in check may one day point researchers toward new ways to ease frailty and bone loss associated with aging, though the evidence so far comes from mice.

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