Western diet-induced MASH in PWK/PhJ mice identifies disruptions in amino acid and sphingolipid metabolism contributing to cardiac dysfunction

Microbial metabolite restores liver health by targeting PPARα and lipid metabolism through the gut-liver axis

This scientific research article reports on the therapeutic potential of a microbial metabolite (10-hydroxy-10-hydr) in alleviating liver in

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Redirecting

Low Sodium in Blood Triggers Anxiety in Mice by Disrupting Their Brain Chemistry

Researchers Reverse Kidney Damage in Mice by Targeting Ceramide-Induced Mitochondrial Damage

Researchers at University of Utah Health discovered that fatty molecules called ceramides trigger acute kidney injury (AKI) by damaging mito

The senescence-stiffening loop: How extracellular matrix remodeling, vascular decline, and mitochondrial dysfunction collectively drive tissue aging

This article presents a unified perspective on tissue aging through a "senescence-stiffening loop" — a self-reinforcing cycle involving extr