Baylor Researchers Discover Molecular Switch That Activates Astrocytes to Clear Alzheimer's Plaques
Summary
Researchers at Baylor College of Medicine discovered that activating a protein called Sox9 in astrocytes (a type of brain cell) triggers them to clear toxic protein plaques associated with Alzheimer's disease. The study, published in Nature Neuroscience, showed that this molecular switch transformed astrocytes into plaque-clearing machines in mice that had already developed memory problems and significant plaque buildup. This finding could fundamentally change approaches to Alzheimer's treatment.
Source
bskyBaylor Researchers Discover Molecular Switch That Activates Astrocytes to Clear Alzheimer's Plaquesflip.itKey quotes
· 3 pulledBy flipping a single molecular switch inside a type of brain cell called an astrocyte, the scientists were able to trigger those cells to physically devour the toxic protein plaques that drive Alzheimer's disease.
The study, published in Nature Neuroscience, found that boosting a protein called Sox9 transformed astrocytes into aggressive plaque-clearing machines.
Researchers at Baylor College of Medicine have discovered something that could fundamentally change how the world thinks about Alzheimer's treatment.
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