Alzheimer's Treatment Clears Brain Plaques in Mice Within Hours
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Summary
Scientists have developed a treatment that repairs the brain's natural gateway system in mice with Alzheimer's-like conditions, allowing amyloid-beta plaques to be cleared away. Within hours of the first injection, mice showed a nearly 45% reduction in these protein clumps, and after three injections, key pathological features of Alzheimer's were reversed in mice genetically engineered to mimic the disease.
Key quotes
· 4 pulledScientists have repaired a natural gateway into the brains of mice, allowing the clumps and tangles associated with Alzheimer's disease to be swept away.
Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease.
After just three drug injections, mice with certain genes that mimic Alzheimer's showed a reversal of several key pathological features.
Sticky protein clumps clog up brain cells in Alzheimer's disease.
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