Transcriptomic and lipidomic analysis of the cryptococcal lung granuloma reveals macrophage boundary programs and sphingolipid remodeling

Pan-cancer AI atlas reveals diversity and spatial organization of tertiary lymphoid structures in tumors

Researchers built a pan-cancer atlas of tertiary lymphoid structures (TLSs) in human tumors, developing an AI-based framework to detect and

Diesel pollution particles impair lysosomal functions of iPSC-derived microglia

DGKζ kinase is essential for CD40-mediated B cell immune synapse formation and antibody production

This study investigates the role of diacylglycerol kinase ζ (DGKζ) in B lymphocytes during CD40-mediated immune responses. The authors demon

Efficient mRNA delivery to resting T cells to reverse HIV latency

Study identifies MD-1 as endogenous agonist for orphan receptor GPRC5B, linking macrophages to adipocyte signaling

This article describes research identifying MD-1 as an endogenous agonist for the orphan G protein-coupled receptor GPRC5B. Using a virion-b

Single-cell map of the healthy human immune system across the lifespan reveals unique infant immune signatures