Single-cell map of the healthy human immune system across the lifespan reveals unique infant immune signatures

Multi-model transcriptomic atlas reveals shared inflammatory programs and epithelial-immune crosstalk in chronic colitis

This study by Fransson, Sorini, et al. presents a multi-model, longitudinal transcriptomic atlas of experimental chronic colitis, integratin

Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming

One billion cells

Next-generation immune models: bioinks, 3D bioprinting, and future directions

An integrative approach for studying immunological variation in an aging population – The Milieu Intérieur follow-up study

Aging impairs antibody responses through defective T follicular helper cell maturation, not B cell dysfunction

This study investigates why antibody responses decline with age in humans. Using tonsil organoids, single-cell RNA sequencing, and CRISPR pe