Small-molecule switches put therapeutic CRISPR editing under on-demand control in living tissues

Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ

Precision gene editing technologies: From proof-of-concept to clinical therapies

This review article examines the evolution of gene therapy from gene addition to precise genome editing, focusing on breakthrough technologi

Cambridge researchers identify NANOG as master gene controlling human embryonic development

Researchers at the University of Cambridge have identified NANOG as the master gene that controls embryonic development in humans. Using CRI

Cambridge researchers identify NANOG as master gene controlling human embryonic development

Researchers at the University of Cambridge have identified NANOG as the master gene that controls embryonic development in humans. Using CRI

Cambridge researchers identify NANOG as master gene controlling human embryonic development

Researchers at the University of Cambridge have identified NANOG as the master gene that controls embryonic development in humans. Using CRI

Phillip Sharp: From RNA Splicing Discovery to RNA-Based Therapeutics

This article profiles Nobel laureate Phillip Sharp, chronicling his pioneering work in RNA splicing discovery and his transition from basic

Columbia University Scientists Achieve Precise Gene Editing in Human Embryos

Scientists at Columbia University have achieved precise gene editing in early human embryos using a newer technique, sparking both hope for

First In-Vivo Gene-Editing Therapy Successfully Saves Newborn's Life in 2025

In 2025, doctors and scientists in the U.S. successfully performed the world's first custom gene-editing therapy inside a living person—a ne