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Cambridge researchers identify NANOG as master gene controlling human embryonic development

By

Michael Le Page

3h ago· 6 min readenNews

Summary

Researchers at the University of Cambridge have identified NANOG as the master gene that controls embryonic development in humans. Using CRISPR base editing to make precise changes to fertilized eggs, they discovered that NANOG acts as a switch that initiates the developmental program for cells to form a human body. The discovery could improve IVF success rates and advance stem cell research and regenerative medicine.

Source

bskyCambridge researchers identify NANOG as master gene controlling human embryonic developmentnewscientist.com

Key quotes

· 2 pulled
The other reason we study these early stages of human development is that it has really profound importance for stem cell biology
A better understanding will help stem cell research and regenerative medicine
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We have identified the gene that, when activated, initiates the developmental programme that results in cells forming a human body

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