Drug combination cools body temperature to reduce stroke-induced brain damage in animal studies
By
Alice Klein
Summary
A combination of two drugs (one for hay fever, one for psychosis) successfully cooled the core body temperature of mice and monkeys, reducing brain damage after stroke by inducing a hibernation-like state. The drugs have undergone preliminary human testing and will proceed to a follow-up clinical trial. This approach aims to limit brain damage by reducing oxygen and glucose needs of brain cells after a stroke.
Source
Twitter / XDrug combination cools body temperature to reduce stroke-induced brain damage in animal studiesnewscientist.comKey quotes
· 3 pulledResearchers have spent decades investigating ways to chill people's brains after they have a stroke to try to limit the damage.
The idea is to freeze brain cells in a hibernation-like state so they don't need as much oxygen and glucose when a stroke occurs.
A combination of two drugs used to treat hay fever and psychosis cooled down the core body temperature of mice and monkeys, reducing brain damage after a stroke.
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