University of Michigan researchers develop technique to map cell-to-cell communication using spatial transcriptomics
By
Kelly Malcom
Summary
A new University of Michigan study published in Nature Genetics introduces a computational technique that uses spatial transcriptomics to infer which cells are communicating with each other in tissue. By mapping where genes are expressed in tissue, the method allows researchers to trace cell-to-cell signaling, solving a long-standing challenge in biology. This breakthrough could deepen understanding of how cells coordinate functions in health and disease.
Source
bskyUniversity of Michigan researchers develop technique to map cell-to-cell communication using spatial transcriptomicsmichiganmedicine.orgKey quotes
· 3 pulledA new U-M study, featured in Nature Genetics, details a technique to infer cell-cell communication using spatial transcriptomics: basically, a map that shows where genes are expressed in the body's tissue.
But while texts and phone calls can be traced to figure out who is talking to whom, determining which cell is talking to which is exceedingly difficult—until now.
People communicate with each other, sometimes face to face, sometimes with a text message or phone call. Cells also communicate with each other, sometimes by touching and sometimes by sending signals across space and time.
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