Mitochondrial quality control in human ageing and longevity

Method to reverse cellular ageing is about to be tested in humans

Study Identifies Phosphatidylcholine Loss as Driver of Mitochondrial Aging, Shows Reversal Possible

Scientists have discovered that the loss of phosphatidylcholine, a membrane lipid essential for mitochondrial flexibility and connectivity,

Energy constraint model of human health: How metabolic trade-offs shape aging and disease

This article presents an energy constraint model of human health, arguing that the body-brain system operates under an economy of energy due

Energy constraint model of human health: How metabolic trade-offs shape aging and disease

This article presents an energy constraint model of human health, arguing that the body-brain system operates under an economy of energy due

Ovarian biology as a blueprint for rejuvenation: Exploring germline immortality and somatic longevity

This essay reframes ovarian biology as a model for rejuvenation rather than solely as a site of reproductive decline. It explores how oocyte

Mechano-metabolic feedback connects tissue fluidity to mitochondrial DNA–dependent immunity in breast cancer

Harvard Scientists Develop Genetic Clock That Measures Biological Aging Across Species

Harvard scientists have developed a new "genetic clock" that measures biological age at the cellular level, going beyond chronological age t