Mechano-metabolic feedback connects tissue fluidity to mitochondrial DNA–dependent immunity in breast cancer
3d ago· 1 min readNews
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RAB5A elevates endocytosis, fluidizes tissue, triggering stress that disrupts AMPK-AKAP1-DRP1, elongating mitochondria, linking fluidity to immune responses in breast cancer. PMID:42129220, Nat Commun 2026, @NatureComms #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
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