Flow-mediated endothelial remodeling and inflammation drive developmental vascular susceptibility in ldlr loss of function

The senescence-stiffening loop: How extracellular matrix remodeling, vascular decline, and mitochondrial dysfunction collectively drive tissue aging

This article presents a unified perspective on tissue aging through a "senescence-stiffening loop" — a self-reinforcing cycle involving extr

Study reveals molecular mechanism linking statins to muscle side effects via NLRP3 inflammasome and protein-prenylation pathway

This scientific research article investigates the molecular mechanisms behind statin-associated myopathy (muscle side effects). The study fi

Fluoxetine disrupts cholesterol metabolism in endothelial cells via SREBP2 activation

Cardiovascular Disease Prevention Through Pharmaceutical LDL Reduction

The article argues that cardiovascular disease (CVD) is effectively a solved problem due to modern pharmaceutical interventions. It explains

Gut Bacteria Molecule Linked to Atherosclerosis, Major Cause of Heart Disease

Spanish scientists discovered that gut bacteria produce a molecule leading to atherosclerosis, a major cause of heart attacks and strokes. T

New plasma proteomics model improves thrombosis risk prediction in cancer patients and identifies IL-17-driven endothelial activation as therapeutic target

This article presents research by Karagkouni and colleagues who developed a new cancer-associated venous thromboembolism (VTE) prediction mo