Aneuploidy selects for the acquisition of driver genes in breast cancer
By
Daniel Schramek
19h agoen
Source
Nature CommunicationsAneuploidy selects for the acquisition of driver genes in breast cancernature.comNature, Published online: 08 July 2026; doi:10.1038/s41586-026-10752-9 Screening of chromosome arm-level aneuploidies uncovers that these alterations select for specific basal-like breast cancer driver genes, including PLGRKT, an oncogene whose tumour-promoting activity is associated with highly stress-resistant mitochondria and enhanced detoxification of reactive oxygen species.
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