ZNF274 constrains lineage plasticity and drives intrinsic resistance to CDK7 inhibitors in pancreatic cancer
12d ago1 min readNews
From the article
ZNF274 limits pancreatic cancer plasticity by maintaining chromatin and suppressing genes. Loss of ZNF274 shifts from classical to invasive basal subtype. PMID:42177198, Nat Commun 2026, @NatureComms #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
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