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Lab Study Finds Compound Stops 90% of Pancreatic Cancer Cell Migration

By

David Nield

2d ago· 5 min readenNews

Summary

Researchers at Florida A&M University have discovered that compounds called polyisoprenylated cysteinyl amide inhibitors can stop 90% of pancreatic cancer cell migration in lab tests. This is significant because pancreatic ductal adenocarcinoma, driven by KRAS gene mutations, has been notoriously difficult to treat — with KRAS long considered "undruggable." The study offers a potential new approach to tackling one of the deadliest cancers.

Source

Twitter / XLab Study Finds Compound Stops 90% of Pancreatic Cancer Cell Migrationsciencealert.com

Key quotes

· 3 pulled
They've long been considered so challenging to treat that KRAS has been labeled 'undruggable' across decades of prior research.
Now, a new lab study points to a possible way around that problem.
A team from Florida A&M University College of Pharmacy and Pharmaceutical Sciences has been testing compounds called polyisoprenylated cysteinyl amide
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Pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer, is particularly deadly and hard to treat.

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