Accelerated Biological Aging in Adults with Congenital Heart Disease: Clinical Evidence and Implications
Summary
This article from the American College of Cardiology examines the emerging evidence of accelerated biological aging in adults with congenital heart disease (CHD). It distinguishes between chronological age (time since birth) and biological age (functional, cellular, and tissue age), noting that accelerated biological aging occurs when biological age exceeds chronological age. The article highlights that in heart disease, accelerated biological aging is linked to a fourfold increased risk of death and hospitalization, particularly in heart failure patients. It explores how the congenital heart disease population may experience premature aging due to chronic physiological stressors, and discusses the clinical implications for managing these patients as they grow older.
Source
Twitter / XAccelerated Biological Aging in Adults with Congenital Heart Disease: Clinical Evidence and Implicationsacc.orgKey quotes
· 4 pulledAging is a major risk factor for most diseases, and accelerated biological aging is increasingly recognized in many chronic diseases.
Chronological age refers to the time that has elapsed since birth, whereas biological age reflects functional, cellular, and tissue age.
Accelerated biological aging is when one's biological age outpaces chronological age.
In heart disease, accelerated biological aging has been linked to heart failure with a fourfold increased risk of death and hospitalization.
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