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Molecular Biology articles

Mitochondrial allostatic load as a molecular bridge between autism and mental health comorbidities

Molecular autism research is evolving towards a biopsychosocial framework that is more informed by autistic experiences. In this context, research aims are m...

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frontiersin.org·Science·6d ago·51 min read

Long-term single-molecule imaging reveals ErbB receptor dimerization dynamics and oncogenic dysregulation

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cell.com7d ago

Open science pioneer Steven Henikoff on sharing protocols and advancing molecular biology research

educationscience

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springernature.com11d ago

MYB transcription factor drives enhancer activation and promoter interactions in acute lymphoblastic leukemia

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doi.org21d ago

Shortened TDP-43 isoforms form steric zippers driving aggregation and mislocalization in ALS pathology

Prion-like domain (PrLD)–mediated aggregation and concomitant dysfunction of the essential RNA-binding protein transactive response (TAR) DNA-binding protein of 43 kilodaltons (TDP-43) is a common ...

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science.org·Twitter Science (trending)·22d ago·70 min read

PrimerWeaver: A free browser-based tool for integrated primer design in molecular biology

Abstract. Primer design remains a fundamental yet non-trivial step in modern molecular biology workflows. Although numerous tools are available, they are o

Newstechnologysciencebioinformatics

doi.org·Science·24d ago·21 min read

Short RNA chaperones inhibit TDP-43 aggregation to reduce neurodegeneration in ALS models

Aberrant aggregation of the prion-like RNA binding protein TDP-43 drives several fatal neurodegenerative proteinopathies, including amyotrophic lateral sclerosis (ALS). In this work, we define how ...

Newssciencehealthneuroscience

doi.org·Science·1mo ago·19 min read

Bacterial type II topoisomerases exhibit species-specific DNA cleavage patterns

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academic.oup.com1mo ago

How Cells Pack Miles of DNA Into Microscopic Spaces: The Biology of Molecular Organization

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burrito.bio2mo ago

Human Accelerated Region 1 (HAR1): A Genomic Segment Linked to Human Brain Evolution

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en.wikipedia.org3mo ago