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ESMFold2 AI generates atlas of over 1 billion predicted protein structures, expanding known protein universe

A new open-source AI tool called ESMFold2 has generated the ESM Atlas, a database of over one billion predicted protein structures and billions more protein sequences. This vastly expands the known protein universe, building on the foundation laid by DeepMind's AlphaFold. The too

Newstechnologyscienceartificial intelligence

scientificamerican.com·Tech by Flipboard·1d ago·6 min read

SynCraft web server integrates retrosynthesis and ADMET evaluation for streamlined drug design

Newstechnologysciencebioinformatics

Shared by @shihcheng.bsky.social on Bluesky ↗

doi.org2d ago

RNAanalyzer3: A free open-source webserver for RNA structure and motif analysis

Newstechnologysciencebioinformatics

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doi.org4d ago

ChIP-Atlas 2025 update: Enhanced quality control and expanded epigenomic data-mining platform marks 10-year milestone

Newstechnologysciencebioinformatics

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doi.org4d ago

Technical Blueprint for Computational Assembly of Virtual Humans from Genomic Principles

Newstechnologysciencebioinformatics

zenodo.org4mo ago

Phage Explorer: Open-Source Software for Bacteriophage Genome Visualization and Analysis

technologysciencebioinformatics

phage-explorer.org4mo ago

Anatomy of BoltzGen: A Hugging Face Space Tool for Protein Design and Binding

Newstechnologysciencebioinformatics

huggingface.co4mo ago

GeneGuessr: Daily Protein Identification Game Based on 3D Structure Analysis

GeneGuessr is a daily protein guessing game where players use clues about protein domains, biological pathways, and molecular functions to identify genes from 3D protein structures. The game combines scientific knowledge with puzzle-solving elements.

Newseducationsciencebioinformatics

geneguessr.brinedew.bio·Hacker News: Front Page·5mo ago·1 min read

Open Human Ontology: Building a Comprehensive Computational Model of Human Biology

The Open Human Ontology is a collaborative project building a comprehensive computational model of human biology using Rust's type system. The project aims to create an accurate, type-safe model of the human body for simulation, analysis, and diagnosis of biological systems. Curr

Codescienceprogrammingbioinformatics

github.com·Hacker News: Front Page·7mo ago·4 min read

Understanding the Burrows-Wheeler Transform: An Interactive Guide to Data Compression and Sequence Alignment

This article provides an interactive introduction to the Burrows-Wheeler Transform (BWT), explaining its core concepts and practical applications. It covers how the BWT works by creating rotations of input strings, sorting them, and extracting the last column to create the transf

technologyprogrammingbioinformatics

sandbox.bio·Hacker News: Front Page·7mo ago·4 min read