Ultrasound microbubbles open blood-brain barrier to deliver cancer drugs in children, pilot study finds
By
Anita Chakraverty
Summary
A pilot study in children has demonstrated that ultrasound-created microbubbles can temporarily open the blood-brain barrier, allowing anti-cancer drugs to reach tumors in difficult-to-access areas like the brain stem and spinal cord. This focused ultrasound (FUS) technique offers a potential new pathway for treating childhood central nervous system cancers that were previously considered untreatable due to the brain's natural protective barrier.
Source
bskyUltrasound microbubbles open blood-brain barrier to deliver cancer drugs in children, pilot study findsinsideprecisionmedicine.comKey quotes
· 3 pulledUltrasound-created microbubbles can deliver anti-cancer drugs to tumors in difficult-to-reach areas such as the brain stem and spinal cord, a pilot study in children has revealed.
The microbubbles provide a potential entry point for treatments aimed at the central nervous system that are not usually able to traverse the blood-brain barrier.
Focused ultrasound (FUS) radiation temporarily opened this naturally protective barrier, which is designed to filter out molecules above a certain size to prevent toxins and infectious agents from entering the brain.
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