Structural basis and physiological significance of non-canonical Gs coupling to the melatonin MT1 receptor

DHEA-S hormone linked to shorter lifespan in men, but not women

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Structural insights into cone opsins reveal the molecular basis of human daylight vision

This article details the molecular basis of human daylight (photopic) vision, focusing on cone opsins — specialized G protein-coupled recept

Study identifies MD-1 as endogenous agonist for orphan receptor GPRC5B, linking macrophages to adipocyte signaling

This article describes research identifying MD-1 as an endogenous agonist for the orphan G protein-coupled receptor GPRC5B. Using a virion-b

Study Links Long-Term Melatonin Use to Increased Heart Failure and Mortality Risks

A preliminary study presented at the American Heart Association's Scientific Sessions 2025 found that long-term melatonin use (one year or l

Texas A&M study identifies NR4A1 receptor activation as key mechanism behind coffee's health benefits

New research from Texas A&M University reveals that compounds in coffee may activate the NR4A1 receptor in the body, a protein linked to agi