Restoring cortical disinhibition improves Huntington’s disease phenotypes

Mouse study shows neurons can recover after autophagy suppression is reversed

Researchers developed a mouse model where autophagy (a key cellular waste-cleaning process) can be reversibly switched on and off. Suppressi

Advances in Brain-on-a-Chip and BBB-on-a-Chip Models for Neurodegenerative Disease Research

This article reviews recent progress in brain-on-a-chip and blood-brain barrier (BBB)-on-a-chip microphysiologic platforms for modeling neur

Huntington's disease treatment shows success in slowing progression for first time, UK trial finds

For the first time, doctors have successfully treated Huntington's disease, a devastating inherited neurodegenerative condition that kills b

A mosaic of whole-body representations on the human precentral gyrus

Basal forebrain PV neurons, not cholinergic neurons, drive sustained attention in mice

This article presents a scientific study on the neural circuits underlying sustained attention in mice. It identifies parvalbumin-expressing

Comparative analysis of the cellular landscape in mammalian striatum