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Plasma proteomic signatures enable risk prediction of early retinal neurodegeneration in type 2 diabetes

By

Huangdong Li ,

13d ago· 53 min readenInsight

Summary

This multi-cohort prospective observational study by Wei Wang and colleagues investigates circulating plasma protein signatures associated with diabetic retinal neurodegeneration (DRN) in type 2 diabetes mellitus. The researchers integrated high-throughput plasma proteomics with longitudinal optical coherence tomography (OCT) in two independent populations to identify protein biomarkers and translate them into a risk prediction system for early retinal neurodegeneration in diabetic patients.

Source

bskyPlasma proteomic signatures enable risk prediction of early retinal neurodegeneration in type 2 diabetesplos.io

Key quotes

· 2 pulled
In this multi-cohort prospective observational study, we integrated high-throughput plasma proteomics with longitudinal optical coherence tomography (OCT) in two independent populations.
Wei Wang and colleagues identify circulating plasma protein signatures of diabetic retinal neurodegeneration (DRN) and translate them into a risk prediction system.
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In a observational multi-cohort study, Wei Wang and colleagues identify circulating plasma protein signatures of diabetic retinal neurodegeneration (DRN) and translate them into a risk prediction system.

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