Network-driven discovery of repurposable drugs targeting hallmarks of aging

Cellular reprogramming emerges as a promising but unproven approach to reversing aging

The article explores "reprogramming" as a buzzy new approach to reversing aging, focusing on cellular reprogramming techniques that aim to r

Facilitating structure-based drug discovery with an artificial intelligence-driven virtual screening platform

Hallmarks of Cancer: A 25-Year Retrospective and Future Directions in Tumor Biology

This review by Douglas Hanahan revisits the "hallmarks of cancer" framework originally conceived with Bob Weinberg 25 years ago. It synthesi

Deep-learning platform GPS enables de novo drug discovery by predicting transcriptomic perturbations from chemical structures

This paper presents GPS (gene expression profile predictor on chemical structures), a deep-learning-based drug discovery platform that scree

Method to reverse cellular ageing is about to be tested in humans

Integrated network analysis maps cross-domain drivers of Alzheimer's disease risk

This article presents a research study on Alzheimer's disease (AD) that uses integrated network analysis to map cross-domain drivers of AD r