Teen becomes first person saved by CRISPR base editing after leukaemia treatment
By
Alyssa Tapley
Summary
13-year-old Alyssa Tapley, diagnosed with leukaemia, was told she had only weeks to live after a failed bone marrow transplant. She became the first person to receive an experimental CRISPR base editing treatment at Great Ormond Street Hospital in London. The procedure, which involved editing immune cells to attack her cancer, saved her life. Now 15 and in remission, she shares her story of survival and the groundbreaking gene-editing therapy that transformed her prognosis.
Source
Key quotes
· 5 pulledWhen the bone marrow transplant failed to treat my leukaemia, it was like: this is it, there's nothing else now.
The doctors were telling my parents it was a matter of weeks. Not years, not months, but weeks.
Oh my gosh, this is my last birthday. I'm never gonna grow up and have a family and do all the things that normal people are completely used to.
It was like sci-fi. They were like: 'Oh, we're gonna take your blood, edit it, and put it back in.'
I'm the first person whose life was saved by CRISPR base editing.
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