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COMMBAT: A web platform for analyzing expression control of biosynthetic gene clusters in bacteria

By

Ribeiro Monteiro, Silvia, Rigolet, Augustin, Jeunehomme, Clément, Gathot, Julianne, Kerdel, Yasmine, Henry, Matthias, Augustijn, Hannah E, Medema, Marnix H, van Wezel, Gilles P, Rigali, Sébastien

15d ago· 17 min readenInsight

Summary

This article presents COMMBAT, a web platform designed to explore expression control of biosynthetic gene clusters (BGCs) in bacterial genomes. BGCs are responsible for producing structurally diverse natural products. The platform provides tools for analyzing and understanding how these gene clusters are regulated at the expression level, enabling researchers to study natural product biosynthesis more effectively.

Source

bskyCOMMBAT: A web platform for analyzing expression control of biosynthetic gene clusters in bacteriadoi.org

Key quotes

· 3 pulled
Bacterial genomes contain thousands of biosynthetic gene clusters (BGCs) responsible for the production of structurally diverse natural products
COMMBAT provides a web platform for exploring expression control of biosynthetic gene clusters
The platform enables researchers to study natural product biosynthesis more effectively
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Abstract. Bacterial genomes contain thousands of biosynthetic gene clusters (BGCs) responsible for the production of structurally diverse natural products

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