Study Links Glucosamine Supplement to Faster Cognitive Decline in People With Mild Cognitive Impairment
By
Megan Brooks
Summary
A new study analyzing electronic health records found that glucosamine, a popular joint supplement, was associated with a 25% higher likelihood of progression from mild cognitive impairment (MCI) to dementia over 5 years. Experiments in human brain tissue and mouse models suggest that excessive protein glycosylation may contribute to Alzheimer's disease progression, and glucosamine supplementation could exacerbate this process. The research identifies glycan metabolism as a potential new therapeutic target for Alzheimer's disease.
Source
Twitter / XStudy Links Glucosamine Supplement to Faster Cognitive Decline in People With Mild Cognitive Impairmentmdsc.peKey quotes
· 3 pulledGlucosamine use was associated with a 25% higher likelihood of progression from MCI to dementia over 5 years.
Experiments in human brain tissue and mouse models suggested that excessive protein glycosylation may contribute to Alzheimer's disease progression.
Glucosamine supplementation could exacerbate the progression of Alzheimer's disease through excessive protein glycosylation.
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