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Alkyl-alkyl cross-coupling preserves stereochemistry in chiral carboxylic acids

By

Bethany Halford

1h ago· 2 min readenNews

Summary

This article discusses advances in synthetic organic chemistry, specifically focusing on cross-coupling reactions that connect two sp3 carbons while preserving stereochemistry. It highlights the importance of alkyl-alkyl cross-coupling as a variation on the Curtius rearrangement, a hot research area for constructing complex compounds efficiently.

Source

bskyAlkyl-alkyl cross-coupling preserves stereochemistry in chiral carboxylic acidscen.acs.org

Key quotes

· 2 pulled
Synthetic organic chemists love their cross-coupling reactions, in which they quickly construct a complex compound by connecting two different, simpler structures.
Building bonds of this type between two sp3 carbons has been a hot area of research
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Alkyl-alkyl cross-coupling is a variation on the Curtius rearrangement

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