Mayo Clinic researchers map molecular structure of PKCβ protein linked to cancer and neurological disorders
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brittanycordeiro
Summary
After nearly four decades of research, Mayo Clinic scientists have mapped the molecular structures of protein kinase C beta (PKCβ), a protein critical for cell communication that is linked to cancer and neurological diseases. Published in Nature Communications, the study provides the first detailed view of how PKCβ works and how the breast cancer drug endoxifen can target it, opening potential pathways for new drug development.
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Key quotes
· 3 pulledAfter nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.
The findings, published in Nature Communications, provide the first detailed view of how the protein works and how the breast cancer drug endoxifen can target this protein.
PKCs are a family of proteins that help cells communicate. They act as molecular switches that...
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