A Rahman Syndrome mutation in histone H1.4 disrupts chromatin compaction and phase separation

Taking apart the DNA-methylation clock with an epigenetic progeria syndrome

New CRISPR Technique Selectively Destroys Cancer Cells with Common Mutation

Researchers at UC Berkeley, UCSF, and Gladstone Institutes have developed a novel CRISPR-based technique called "RNA-Triggered Chromatin Shr

Replication-stress-induced chromatin loops protect fork stability

Study Challenges Decades-Old View That DNA Is Locked Away When Wrapped Around Nucleosomes

A new study from Gladstone Institutes and the Arc Institute challenges the long-held belief that DNA wrapped around nucleosomes is locked aw

Epigenetic clocks as quantitative readouts of epigenetic drift

Nature research paper: Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource