Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella -containing vacuole
Legionella pneumophila ( L.p .), an intracellular bacterial pathogen, hijacks the ubiquitin signaling network of its eukaryotic host cells to establish infection. Two families of L.p . secreted ubiquitin ligases are instrumental in the maturation of the Legionella -containing vacuole (LCV): the SidC/SdcA family, which catalyzes canonical ubiquitination, and