Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella -containing vacuole
Legionella pneumophila ( L.p .), an intracellular bacterial pathogen, hijacks the ubiquitin signaling network of its eukaryotic host cells to establish infection. Two families of L.p . secreted…
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Design principles of a membrane-spanning ubiquitin ligase
I think this complex is very cool! Excited to see this in print @jennkong.bsky.social! 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00344-2
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Seven individuals from five families harboring monoallelic PSMB8 variants presented with immunodeficiency and systemic inflammation. Mutant

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