First human treated in gene therapy trial aiming to reverse cellular aging through partial reprogramming
By
Heidi Ledford
Summary
A landmark clinical trial has begun treating the first human participant with a gene therapy that aims to reverse cellular aging. The approach involves activating three genes to "partially reprogram" aged cells, making them behave younger. The initial application targets glaucoma, a blindness-causing disease, with the broader hope that this technique could eventually rejuvenate old organs.
Source
bskyFirst human treated in gene therapy trial aiming to reverse cellular aging through partial reprogrammingscientificamerican.comKey quotes
· 3 pulledTest time has arrived: the first person has been treated in a highly anticipated gene therapy trial that aims to coax aged cells to take on a younger identity.
The clinical trial will test a novel approach that involves turning on three genes that seem to 'partially reprogram' old cells, allowing them to behave as if they were young again.
Some scientists argue that partial reprogramming could rejuvenate old organs.
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