The aging extracellular matrix as a missing link in senescent cell accumulation and persistence

Method to reverse cellular ageing is about to be tested in humans

Toward a life-course biology of aging: How early-life conditions shape late-life health and longevity

This article proposes a "life-course biology of aging" framework, arguing that aging is not solely determined by current conditions but is s

Plasma proteomic signatures of cellular aging predict human disease - Nature Medicine

Ageing Acceleration Around Age 50: Study Reveals Tissue Changes

An analysis reveals that ageing of tissues accelerates around age 50, with an inflection point where ageing speeds up, especially in blood v

Ovarian biology as a blueprint for rejuvenation: Exploring germline immortality and somatic longevity

This essay reframes ovarian biology as a model for rejuvenation rather than solely as a site of reproductive decline. It explores how oocyte

Study reveals how chronic inflammation drives age-associated CD8+ T cell remodeling

This study by Shchukina et al. investigates how aging and chronic low-grade inflammation remodel the CD8+ T cell compartment. The researcher