Profiling the molecular and physiological effects of senolytic treatment on aged mice identifies immune, fibrotic and metabolic remodeling

Senolytic treatment linked to oligodendrocyte dysfunction and demyelination in brain study

This scientific research article investigates the effects of senolytic treatment (dasatinib and quercetin combination) on the corpus callosu

SIRT6 overexpression counteracts chromatin aging in the male murine liver

Method to reverse cellular ageing is about to be tested in humans

Aged circulating CD8+ T cells and their secreted factor granzyme K drive cognitive decline in mice

This study investigates how aged circulating CD8+ T cells contribute to cognitive decline without infiltrating the brain. Using heterochroni

Study reveals how chronic inflammation drives age-associated CD8+ T cell remodeling

This study by Shchukina et al. investigates how aging and chronic low-grade inflammation remodel the CD8+ T cell compartment. The researcher

Stanford Study: Restoring Gut-Brain Communication Reverses Cognitive Decline in Aging Mice

Stanford Medicine researchers discovered that aging-related changes in gut bacteria composition trigger an inflammatory response that impair