Placenta accreta spectrum: Challenging traditional views and redefining a dangerous pregnancy disorder

This article discusses Placenta accreta spectrum (PAS), a disorder of placentation where placental villous tissue abnormally attaches to the uterine myometrium. When unrecognized at birth, attempts at manual placental removal can cause massive hemorrhage and significant maternal morbidity and mortality. The article traces the condition from its first description by Irving and Hertig in 1937 to current 21st-century understanding, challenging existing dogma and redefining how the disorder is conceptualized and managed.

Eric Jauniaux ,23d ago9 min readenInsight

science health medical research obstetrics

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Key quotes

Placenta accreta spectrum (PAS) is a disorder of placentation characterized by the abnormal attachment of part of the placenta villous tissue to the uterine myometrium.

When unrecognized at birth, attempts at manual placental removal can precipitate massive hemorrhage and significant maternal morbidity and mortality.

First described by Irving and Hertig in 1937, PAS was defined clinically as abnormal placental adherence at delivery and histologically...

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