Mouse study finds 7% of epigenetic marks are inherited outside Mendelian rules
By
Vanessa Wasta
Summary
A new federally funded study using mice reveals that approximately 7% of epigenetic marks—chemical modifications to DNA that don't alter the DNA code itself—can be inherited in ways that break traditional Mendelian inheritance rules. This challenges the century-long understanding of genetic inheritance established by Gregor Mendel's work with pea plants, showing that non-DNA-coded traits can be passed down through mechanisms beyond classical genetics.
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Key quotes
· 3 pulledScientists have long known that the DNA code in genes is not the only way to pass genetic traits from parents to offspring.
Epigenetic marks—chemical modifications to DNA that don't change the DNA code itself—can also be passed down.
The study reveals that some of those marks—about 7% of them—can be inherited in ways that break the century-long understanding of the rules of inheritance explored and recorded by Gregor Mendel's work with pea plants.
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