GLP-1 drugs like Ozempic may improve mood by altering gut microbiome, study suggests
By
Scott C. Anderson
Summary
Recent research from Southeast University in China, led by Honghong Yao, suggests that GLP-1 drugs like Ozempic may improve mood in depressed patients by altering the gut microbiome. The study connects the weight-loss effects of these drugs to changes in gut bacteria, which in turn influence brain chemistry and mood regulation. The findings imply that some of these antidepressant benefits might also be achievable through dietary changes that similarly impact the gut microbiome.
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Key quotes
· 3 pulledI've been taking Ozempic to lose weight but now I want to go hiking and play badminton with my friends.
Researchers rejoiced when Ozempic and other GLP-1 drugs worked to shed weight in their patients. But there was an unexpected bonus: Some depressed patients started to feel better.
They pieced together several related observations to solve the mystery.
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