Systematic Review Finds GLP-1 Agonists Do Not Harm Male Fertility, May Offer Benefits
By
Miriam E. Tucker
Summary
A systematic review presented at a medical conference found that GLP-1 agonists (like Ozempic, Wegovy) do not harm male fertility or the male reproductive axis. The review, which analyzed three randomized controlled trials, found no negative long-term effects on the hypothalamic-pituitary-gonadal axis and some evidence suggesting potential fertility benefits. Study author Dr. Pratibha Natesh noted the data is still sparse but sufficient to counsel patients that these drugs don't negatively impact the reproductive system.
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Key quotes
· 3 pulledOne thing we proved is that they do not harm the reproductive axis in men. There was no inhibitory effect, so we can counsel our patients that the drugs don't impact the reproductive system negatively.
We only found three randomized control
Current evidence does not show a negative long-term effect of GLP-1 agonists on male fertility, and some data suggest the drugs may offer benefits
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