Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells

AI-guided discovery identifies GPNMB as promising CAR T cell target for multiple cancers

Researchers developed an AI-driven framework for discovering CAR T cell therapy targets by integrating single-cell RNA sequencing data from

Antibody-ligand motif optimization enables multitarget switchable CAR-T therapy against solid tumors

This article presents a research study on optimizing a multitarget switchable CAR-T (sCAR-T) strategy to overcome antigenic heterogeneity an

Tumor-targeted interferon-α gene therapy for glioblastoma: a phase 1 trial

China approves world's first CAR-T cell therapy for solid tumors: CARsgen's satri-cel for advanced gastric cancer

CARsgen Therapeutics has received approval from China's NMPA for satricabtagene autoleucel (satri-cel; CT041), the world's first CAR-T cell

Proteomic and phosphoproteomic profiling reveals melanoma cell responses to T cell attack

This study profiles the early proteomic and phosphoproteomic responses of patient-derived melanoma cells when co-cultured with matched autol

Study finds cancer-associated somatic mutations in brain immune cells linked to Alzheimer's neuroinflammation

This study investigates the link between Alzheimer's disease (AD) and somatic mutations in brain immune cells. Deep sequencing of 311 brain