DNA-PK-mediated CRTC2 phosphorylation promotes NHEJ and suppresses antitumor immunity via relocation to repair complexes

Cdh1 stabilizes STING to boost innate immune activation in renal cell carcinoma, study finds

This article presents research by Zhu et al. on the role of the APC/C adaptor protein Cdh1 in stabilizing STING (a key innate immune sensor)

New CRISPR Technique Selectively Destroys Cancer Cells with Common Mutation

Researchers at UC Berkeley, UCSF, and Gladstone Institutes have developed a novel CRISPR-based technique called "RNA-Triggered Chromatin Shr

Efficient mRNA delivery to resting T cells to reverse HIV latency

DDX6 helicase suppresses innate immune responses by disrupting endogenous double-stranded RNA stability in cancer cells

This research article reveals that DEAD-box RNA helicase 6 (DDX6) interacts with ADAR1 to repress editing of A:C mismatches in double-strand

Programming the immunological properties of mRNA vaccines for cancer

Vitamin C Promotes Epidermal Proliferation by Promoting DNA Demethylation of Proliferation-Related Genes in Human Epidermal Equivalents