Chaperone-mediated autophagy is required for regulatory T cell function

Study reveals how immunotherapy can drive immune evasion in pancreatic cancer through Treg cell activity and MHC-I suppression

This study investigates mechanisms driving immunotherapy resistance in pancreatic ductal adenocarcinoma (PDA). Using murine models, the rese

Study reveals CXCL16-driven γδ T cell brain infiltration reduces sociability in autism mouse model

This study investigates the role of immune cells, specifically γδ T cells, in autism spectrum disorder (ASD) using a mouse model of 15q11-13

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Efficient mRNA delivery to resting T cells to reverse HIV latency

Study reveals CXCL16-driven γδ T cell brain infiltration reduces sociability in autism mouse model

This study investigates the role of lymphocytes, specifically γδ T cells, in neurodevelopmental disorders using a mouse model of 15q11-13 du

Study reveals CXCL16-driven γδ T cell brain infiltration reduces sociability in autism mouse model

This study investigates the role of lymphocytes, specifically γδ T cells, in neurodevelopmental disorders using a mouse model of 15q11-13 du

Cdh1 stabilizes STING to boost innate immune activation in renal cell carcinoma, study finds

This article presents research by Zhu et al. on the role of the APC/C adaptor protein Cdh1 in stabilizing STING (a key innate immune sensor)