Iron-catalyzed lipid peroxidation drives rapid coordinated cell death in algal blooms
By
Yi Tao
Summary
This article investigates the mechanism behind the rapid termination of harmful algal blooms. Researchers identified that iron-catalyzed active lipid peroxides trigger coordinated cell death in blooming algae. The process involves glutathione oxidation and iron overload leading to lipid peroxidation, membrane disruption, and cell lysis. Cell death then propagates through the population as oxidized lipids from dying cells damage neighboring cells, explaining the abrupt collapse of algal blooms within days.
Source
Twitter / XIron-catalyzed lipid peroxidation drives rapid coordinated cell death in algal bloomsscim.agKey quotes
· 5 pulledBlooms of toxic algae are a regular feature in many bodies of water, and they often emerge and then subside rapidly.
Glutathione oxidation and iron overload are proposed as initiating factors leading to lipid peroxidation, membrane disruption, and cell lysis.
Cell death then propagates to neighboring cells as oxidized lipids are released and cause damage to other cells in the population.
Harmful algal blooms, the most severe ecological hazards worldwide, terminate abruptly within a few days.
We identified that iron-catalyzed active lipid peroxides predominantly trigger...
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