Study Links Antidepressants and Antidiarrheal Drugs to Slightly Higher Mortality Risk in IBS Patients
By
Marcia Frellick
Summary
A study published in Communications Medicine found that antidepressants and certain antidiarrheal drugs (mu receptor agonists like loperamide and diphenoxylate) are linked to a slightly higher risk for death in adults with irritable bowel syndrome (IBS). The retrospective cohort study used the TriNetX Analytics US EHR database from 2005 to 2023, raising concerns about the safety of these medications in IBS treatment and calling for new considerations in long-term prescribing.
Source
Twitter / XStudy Links Antidepressants and Antidiarrheal Drugs to Slightly Higher Mortality Risk in IBS Patientsmdsc.peKey quotes
· 2 pulledThe findings, published in Communications Medicine, raise concerns about the safety of antidepressants and mu receptor agonists in IBS treatment and call for new considerations in long-term prescribing, the authors wrote.
Researchers performed a retrospective cohort study using the TriNetX Analytics US electronic health record (EHR) database from 2005 to 2023.
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