Trefoil polymers from a knotted synthon
Nature Chemistry, Published online: 29 June 2026; doi:10.1038/s41557-026-02197-4 An overhead knot that serves as a topological synthon enables the high-yield synthesis of trefoiled polymers with precise control over knotting. Topology–property relationships are then investigated across different polymer backbones, and the knotting influence on these properti