Anaerobic gut pathogen ETBF rewires host metabolism to create an oxidative niche for survival in inflamed colon
Enterotoxigenic Bacteroides fragilis (ETBF), a classically anaerobic pathogen, uses its toxin, BFT, to remodel host metabolism and generate a localized oxidative niche in the colon. By shifting epithelial cells toward fermentative metabolism, ETBF increas