LIN28B gene identified as essential for fetal B-cell development and initiation of KMT2A::AFF1 infant leukemia

This scientific research article reports that the fetal-specific gene LIN28B is essential for human fetal B-lymphopoiesis (the development of B cells in the fetus) and plays a critical role in initiating KMT2A::AFF1 infant leukemia, a type of B-cell acute lymphoblastic leukemia (