Molecular glue approach doubles survival time for aggressive pancreatic cancer patients
By
Bloomberg
Warm and crisp on the edges. A bagel with a bit of bite.
Summary
Chemical biologist Gregory Verdine developed a novel approach to fighting cancer by using "molecular glues" to bind disease-causing proteins inside cells and neutralize them. Despite initial skepticism, the technology was acquired by Revolution Medicines Inc., which recently announced a drug that doubled survival time for patients with aggressive pancreatic cancer. The approach represents one of the biggest advances in pancreatic cancer treatment in decades.
Key quotes
· 3 pulledEverybody told us this is crazy, that it would never work.
One of the biggest advances in pancreatic cancer in decades came out of a crazy idea born in a Harvard University lab.
You could fight disease-causing proteins hidden inside cells by chemically gluing them to something else in the body and smothering them.
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